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omicron: Anti-Covid drugs potent against Omicron, antibody therapies less effective: Study

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WASHINGTON: The current drugs to treat Covid-19 remain very effective against the Omicron variant of the SARS-CoV-2 virus, according to a laboratory study. However, available antibody therapies -- typically given intravenously in hospitals -- are substantially less effective against Omicron compared to earlier variants of the virus, the researchers said. The lab tests also showed that some antibodies have entirely lost their ability to neutralise Omicron at realistic dosages, they said. "The bottom line is we have countermeasures to treat Omicron. That's good news," said study lead author Yoshihiro Kawaoka, from the University of Wisconsin–Madison in the US. "However, this is all in laboratory studies. Whether this translates into humans, we don't know yet," Kawaoka said. The findings, published in the New England Journal of Medicine on Wednesday, corroborate other studies that show most available antibody treatments are less effective against Omicron. T...

Breakthrough infections generate strong immunity to Covid-19 variants: Study

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WASHINGTON: People who are infected after getting vaccinated develop a greatly enhanced immune response to variants of the SARS-CoV-2 virus that causes Covid-19, according to a lab study. The research, published in the Journal of the American Medical Association (JAMA), shows that a breakthrough infection generates a robust immune response against the Delta variant. The findings suggest that the immune response in such people is likely to be highly effective against other variants as the SARS-CoV-2 virus continues to mutate. "You can't get a better immune response than this. These vaccines are very effective against severe disease," said study senior author Fikadu Tafesse, an assistant professor at Oregon Health & Science University (OHSU) in the US. "Our study suggests that individuals who are vaccinated and then exposed to a breakthrough infection have super immunity," Tafesse said. The study found that antibodies measured in blood samples of breakthro...